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AFFiRiS releases positive study results of AD04 therapeutic drug in Alzheimer patients AFFiRiS AG of Vienna, Austria, today released for the first time outcomes of a clinical phase II study in Alzheimer patients of its proprietary compound Advertisement04, a therapeutic medication against Alzheimer's disease. The results present an impressive therapeutic effect of AD04 and make it the first ever substance demonstrating scientific and biomarker evidence consistent with disease modification of Alzheimer's disease.