Improper skin cleansing 12. Stress 13. Inadequate rest 14. Alcoholism 15. Tobacco intake 16. Consumption of caffeine. Home Remedies for Acne 1. One may pound orange peel with water and apply the paste on acne break-outs to get rid of acne. 2. Program of lemon juice is an efficient do-it-yourself solution for acne. 3. Intake of 2-3 seeds of raw garlic daily purifies bloodstream and prevents acne. Rubbing natural garlic on pimples heals them up. 4. You can apply a paste made out of coriander leaf juice or any various other mint leaf juice and a pinch of turmeric powder on pimples. This is a beneficial acne remedy. 5. A paste of fenugreek leaves could be applied on acne before retiring to bed at night and washed off with warm water each morning.Discussion The purpose of this trial was to determine if the use of a proton-pump inhibitor, esomeprazole, in doses large enough to suppress gastric acid, would improve asthma control in patients with inadequately controlled asthma who did not have got frequent symptoms of gastroesophageal reflux. We used a dosage of esomeprazole that was greater than that typically used to treat symptomatic gastroesophageal reflux to be able to increase our self-confidence that there was sufficient suppression of gastric acid.42 Moreover, we performed ambulatory esophageal pH-monitoring studies to establish whether individuals with documented acid reflux might benefit more from therapy with a proton-pump inhibitor than persons without documented acid reflux disorder.