Ranging from overeating and drug dependency to neuropathic discomfort.

Daniele Piomelli, professor of pharmacology at the UC Irvine College of Medicine, and co-workers at the University of Connecticut possess developed a molecule, AM1172, that regulates the digesting of a neurotransmitter known as anandamide. In lab tests on mice, Piomelli discovered AM1172 to work in increasing human brain anandamide activity, in much the same way as the antidepressant drug Prozac raises activity of the neurotransmitter serotonin. Related StoriesCharles Bonnet syndrome: an interview with Dr. Dominic carry out we sleep ffytcheWhy? An interview with Professor WisdenBrain health: how can you reduce cognitive decline? An interview with Heather Snyder, Ph.D.The analysis appears in the first online edition of the Proceedings of the National Academy of Sciences, May 10.Lamb, D.Phil., Sanjoy Shah, M.D., Iain MacKenzie, M.D., William Tunnicliffe, M.Sc., Ranjit Lall, Ph.D., Kathy Rowan, D.Phil., and Brian H. Cuthbertson, M.D. For the OSCAR Study Group: High-Regularity Oscillation for Acute Respiratory Distress Syndrome The acute respiratory distress syndrome is a severe, diffuse inflammatory lung condition the effect of a range of acute illnesses. Mortality in affected patients is high,1 and survivors may have useful limitations for years.2,3 Although mechanical ventilation may initially be lifesaving in sufferers with ARDS, additionally, it may further injure the sufferers’ lungs and donate to death.4 High-frequency oscillatory ventilation was initially utilized experimentally in the 1970s to minimize the hemodynamic effects of mechanical ventilation.5 Patients’ lungs are held inflated to keep up oxygenation, and skin tightening and is cleared by small volumes of gas moved in and from the respiratory system at 3 to 15 Hz.