During the follow-up, 1,708 men and 892 females developed cardiovascular system disease. When they divided the men and women into five groups, according to waist-hip ratio, researchers discovered that those with the highest waist-to-hip ratio got the highest cardiovascular disease risk. Among the findings: Men in the top one-fifth of the distribution experienced a 55 % higher risk of developing coronary heart disease compared to men in the bottom one-5th of the distribution .Changes in LDL cholesterol amounts at 24 weeks didn’t differ considerably among the three research groupings in either the modified intention-to-treat people or the per-protocol people . In the modified intention-to-treat population, a reduction in LDL cholesterol amounts was observed in the weight-loss group. In the per-protocol inhabitants, LDL cholesterol amounts were reduced in the combined-intervention group and the weight-loss group however, not in the CPAP group. Changes in HDL cholesterol levels from baseline to 24 weeks were very similar among the three study groups .